科研成果
1.N.J. Hao, X.J. Zhang, “Microfluidic Screening of Circulating Tumor Biomarkers towards Liquid Biopsy”, Separation & Purification Reviews (Taylor & Francis), 2017
2.A. Tadimety, A. Syed, Y. Nie, C. Long, X.J. Zhang, “Liquid Biopsy on Chip: A Paradigm Shift towards the Understanding of Cancer Metastasis”, Integrative Biology, 9, 22 – 49, 2017
3.Y. Zhu, K. Kekalo, C. NDong, Y. Huang, F. Shubitidze, K. Krisword, I. Baker and X.J. Zhang, “Magnetic- nanoparticle-based immunoassays-on-Chip: materials synthesis, surface functionization and cancer cell screening”, Advanced Functional Materials, 26, 3953-3972, 2016.
4.J. Wu, X. Wei, J. Gan, J. Lou, T. Shen, B. Liu, X.J. Zhang*, K. Qian*, “Multi-functional magnetic particles for combined circulating tumor cells isolation and cellular metabolism detection”, Advanced Functional Materials (*co-corresponding authors), 26, 4016-4025, 2016.
5.E. Ng, K. Chen, M. Hang, A. Syed, X.J. Zhang, “Multi-dimensional nanostructure for microfluidic screening of biomarkers: from molecular separation to cancer cell detection”, Annals of Biomedical Engineering, 1-16, 2015.
6.K. Hoshino, H. Chung, C. Wu, K. Rajendran, Y. Huang, P. Chen, K. Sokolov, J. Kim, X.J. Zhang, “Immunofluorescence-assisted microfluidic single-cell quantitative reverse transcription polymerase chain reaction analysis of tumor cells in blood”, Journal of Circulating Biomarkers, Vol. 4:11, 2015. (the most popular research paper published in the journal for the year 2015)
7.P. Chen, Y. Huang, G. Bhave, K. Hoshino, X.J. Zhang, “Inkjet-Print Micromagnet Array on Glass Slides for Immunomagnetic Enrichment of Circulating Tumor Cells”, Annals of Biomedical Engineering, 1-11, 2015
8.Y.-Y. Huang, P. Chen, C.H. Wu, K. Hoshino, K. Sokolov, N. Lane, H. Liu, M. Huebschman, E. Frenkel, X.J. Zhang, “Screening and Molecular Analysis of Single Circulating Tumor Cells Using Micromagnet Array”, Scientific Reports, Nature Publishing Group, 5, 16047, 2015
9.P. Chen, Y-Y Huang, K. Hoshino and X.J. Zhang, “Microscale Magnetic Field Modulation for Enhanced Capture and Distribution of Rare Circulating Tumor Cells”, Scientific Reports, Nature Publishing Group, 5, 8745, doi:10.1038/srep08745, March, 2015
10.P. Chen, Y.-Y. Huang, K. Hoshino, C.-H. Wu, K.V. Sokolov, X.J. Zhang, "Multiscale immunomagnetic enrichment of circulating tumor cells: from tubes to microchips", Lab on a Chip, 14, 446-458, 2014 (Critical Review)
11.Y. Song, Y. Huang, X. Liu, X.J. Zhang, M. Ferrari, L. Qin, “Point-of-care technologies for molecular diagnostics using a drop of blood”, Trends in Biotechnology, review for special issue on “Blood”, 32, 3, p132-139, 2014 (invited review)
12.C.-H. Wu, Y.-Y. Huang, K. Hoshino, P. Chen, H. Liu, E.P. Frenkel, X.J. Zhang, K.V. Sokolov, "Versatile immunomagnetic nanocarrier platform for capturing cancer cells", ACS Nano, 7(10), 8816-8823, 2013
13.E. Ng, K. Hoshino, X.J. Zhang, “Microfluidic Immunodetection of Cancer Cells via Site-Specific Microcontact Printing of Antibodies on Nanoporous Surface”, Methods, 63(3), 266-75, 2013
14.Z.X. Wang, D. Fine, H. Wu, J. Schmulen, Y. Hu, B. Godin, X.J. Zhang, and X. Liu, “Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles”, Lab on a Chip, 13, 2879-2882, 2013
15.Y.Y. Huang, K. Hoshino, P. Chen, C. Wu, N. Lane, M. Huebschman, K. Sokolov, J.W. Uhr, E.P. Frenkel and X.J. Zhang, “Immunomagnetic Nanoscreening of Circulating Tumor Cells with a Motion Controlled Microfluidic System”, Biomedical Microdevices, 15(4):673-81, 2013
16.K. Hoshino, P. Cheng, Y. Huang and X.J. Zhang, “Computational analysis of immunomagnetic rare cell separation from a particulate blood flow”, Analytical Chemistry, 84, 4292-4299, 2012.
17.J. Uhr, M. Huebschman, E.P. Frenkel, N. Lane, H. Liu, D. Rana, L. Cheng, A. Lin, G.A. Hughes, X. J. Zhang, and H. G. Garner, “Molecular Profiling of Individual Tumor Cells by Hyperspectral Microscopic Imaging”, Translational Research – The Journal of Laboratory and Clinical Medicine, 159 (2012), pp. 366-375.
18. K. Hoshino, Y.Y. Huang, N. Lane, M. Huebschman, J.W. Uhr, E.P. Frenkel and X.J. Zhang, “Microchip based Immunomagnetic Detection of Circulating Tumor Cell”, Lab on Chip, 11, 3449-3457, 2011.
a. among the top ten accessed articles of Lab on a Chip in the two consecutive months of August and September 2011.
19.E. Ng, A. Gopal, K. Hoshino, X.J. Zhang, “Multicolor Microcontact Printing of Proteins on Nanoporous Surface for Patterned Immunoassay”, Applied Nanoscience, 1:79-85, 2011.
20.Y. Hu, A. Gopal, K. Lin, Y. Peng, X. J. Zhang, M. Ferrari, “Microfluidic enrichment of small proteins from complex biological mixture on nanoporous silica chip”, Biomicrofluidics (joint-corresponding author), 5, 013410, 2011.
21.E. Blinka, K. Loeffler, Y. Hu, A. Gopal, K. Hoshino, M. Ferrari and X.J. Zhang, “Enhanced microcontact printing of proteins on nanoporous silica surface”, Nanotechnology, 21, 415302, (9pp), 2010.
22. 张晓晶、沈挺. 基于微芯片的自动化循环肿瘤细胞检测系统--CellRichTM新型液体活检平台. 转化医学网（2017.4）
23. 乐飚, 宋毅，沈挺，张晓晶. 液体活检（循环肿瘤细胞）与医学影像学诊断的临床相关性. 转化医学网（2017.6）
24. 乐飚, 宋毅，饶创宙，钱海龙，沈挺，张晓晶. 循环肿瘤细胞检测对胃癌辅助诊断和预后的意义. 转化医学网（2017.7）
25. 乐飚, 宋毅，邬振华，郝敬铎，沈挺，张晓晶. 循环肿瘤细胞检测对头颈部肿瘤诊疗的临床意义. 转化医学网（2017.9）
26. 乐飚, 宋毅，严梅娣，沈挺，张晓晶. 循环肿瘤细胞检测对乳腺癌早期诊断和预后的临床意义. 转化医学网（2017.11）
27. 张晓晶, 沈挺, 宋毅, 张凯岳. 微流控技术在液体活检领域的应用. 转化医学网（2018.1）
2.A. Tadimety, A. Syed, Y. Nie, C. Long, X.J. Zhang, “Liquid Biopsy on Chip: A Paradigm Shift towards the Understanding of Cancer Metastasis”, Integrative Biology, 9, 22 – 49, 2017
3.Y. Zhu, K. Kekalo, C. NDong, Y. Huang, F. Shubitidze, K. Krisword, I. Baker and X.J. Zhang, “Magnetic- nanoparticle-based immunoassays-on-Chip: materials synthesis, surface functionization and cancer cell screening”, Advanced Functional Materials, 26, 3953-3972, 2016.
4.J. Wu, X. Wei, J. Gan, J. Lou, T. Shen, B. Liu, X.J. Zhang*, K. Qian*, “Multi-functional magnetic particles for combined circulating tumor cells isolation and cellular metabolism detection”, Advanced Functional Materials (*co-corresponding authors), 26, 4016-4025, 2016.
5.E. Ng, K. Chen, M. Hang, A. Syed, X.J. Zhang, “Multi-dimensional nanostructure for microfluidic screening of biomarkers: from molecular separation to cancer cell detection”, Annals of Biomedical Engineering, 1-16, 2015.
6.K. Hoshino, H. Chung, C. Wu, K. Rajendran, Y. Huang, P. Chen, K. Sokolov, J. Kim, X.J. Zhang, “Immunofluorescence-assisted microfluidic single-cell quantitative reverse transcription polymerase chain reaction analysis of tumor cells in blood”, Journal of Circulating Biomarkers, Vol. 4:11, 2015. (the most popular research paper published in the journal for the year 2015)
7.P. Chen, Y. Huang, G. Bhave, K. Hoshino, X.J. Zhang, “Inkjet-Print Micromagnet Array on Glass Slides for Immunomagnetic Enrichment of Circulating Tumor Cells”, Annals of Biomedical Engineering, 1-11, 2015
8.Y.-Y. Huang, P. Chen, C.H. Wu, K. Hoshino, K. Sokolov, N. Lane, H. Liu, M. Huebschman, E. Frenkel, X.J. Zhang, “Screening and Molecular Analysis of Single Circulating Tumor Cells Using Micromagnet Array”, Scientific Reports, Nature Publishing Group, 5, 16047, 2015
9.P. Chen, Y-Y Huang, K. Hoshino and X.J. Zhang, “Microscale Magnetic Field Modulation for Enhanced Capture and Distribution of Rare Circulating Tumor Cells”, Scientific Reports, Nature Publishing Group, 5, 8745, doi:10.1038/srep08745, March, 2015
10.P. Chen, Y.-Y. Huang, K. Hoshino, C.-H. Wu, K.V. Sokolov, X.J. Zhang, "Multiscale immunomagnetic enrichment of circulating tumor cells: from tubes to microchips", Lab on a Chip, 14, 446-458, 2014 (Critical Review)
11.Y. Song, Y. Huang, X. Liu, X.J. Zhang, M. Ferrari, L. Qin, “Point-of-care technologies for molecular diagnostics using a drop of blood”, Trends in Biotechnology, review for special issue on “Blood”, 32, 3, p132-139, 2014 (invited review)
12.C.-H. Wu, Y.-Y. Huang, K. Hoshino, P. Chen, H. Liu, E.P. Frenkel, X.J. Zhang, K.V. Sokolov, "Versatile immunomagnetic nanocarrier platform for capturing cancer cells", ACS Nano, 7(10), 8816-8823, 2013
13.E. Ng, K. Hoshino, X.J. Zhang, “Microfluidic Immunodetection of Cancer Cells via Site-Specific Microcontact Printing of Antibodies on Nanoporous Surface”, Methods, 63(3), 266-75, 2013
14.Z.X. Wang, D. Fine, H. Wu, J. Schmulen, Y. Hu, B. Godin, X.J. Zhang, and X. Liu, “Ciliated micropillars for the microfluidic-based isolation of nanoscale lipid vesicles”, Lab on a Chip, 13, 2879-2882, 2013
15.Y.Y. Huang, K. Hoshino, P. Chen, C. Wu, N. Lane, M. Huebschman, K. Sokolov, J.W. Uhr, E.P. Frenkel and X.J. Zhang, “Immunomagnetic Nanoscreening of Circulating Tumor Cells with a Motion Controlled Microfluidic System”, Biomedical Microdevices, 15(4):673-81, 2013
16.K. Hoshino, P. Cheng, Y. Huang and X.J. Zhang, “Computational analysis of immunomagnetic rare cell separation from a particulate blood flow”, Analytical Chemistry, 84, 4292-4299, 2012.
17.J. Uhr, M. Huebschman, E.P. Frenkel, N. Lane, H. Liu, D. Rana, L. Cheng, A. Lin, G.A. Hughes, X. J. Zhang, and H. G. Garner, “Molecular Profiling of Individual Tumor Cells by Hyperspectral Microscopic Imaging”, Translational Research – The Journal of Laboratory and Clinical Medicine, 159 (2012), pp. 366-375.
18. K. Hoshino, Y.Y. Huang, N. Lane, M. Huebschman, J.W. Uhr, E.P. Frenkel and X.J. Zhang, “Microchip based Immunomagnetic Detection of Circulating Tumor Cell”, Lab on Chip, 11, 3449-3457, 2011.
a. among the top ten accessed articles of Lab on a Chip in the two consecutive months of August and September 2011.
19.E. Ng, A. Gopal, K. Hoshino, X.J. Zhang, “Multicolor Microcontact Printing of Proteins on Nanoporous Surface for Patterned Immunoassay”, Applied Nanoscience, 1:79-85, 2011.
20.Y. Hu, A. Gopal, K. Lin, Y. Peng, X. J. Zhang, M. Ferrari, “Microfluidic enrichment of small proteins from complex biological mixture on nanoporous silica chip”, Biomicrofluidics (joint-corresponding author), 5, 013410, 2011.
21.E. Blinka, K. Loeffler, Y. Hu, A. Gopal, K. Hoshino, M. Ferrari and X.J. Zhang, “Enhanced microcontact printing of proteins on nanoporous silica surface”, Nanotechnology, 21, 415302, (9pp), 2010.
22. 张晓晶、沈挺. 基于微芯片的自动化循环肿瘤细胞检测系统--CellRichTM新型液体活检平台. 转化医学网（2017.4）
23. 乐飚, 宋毅，沈挺，张晓晶. 液体活检（循环肿瘤细胞）与医学影像学诊断的临床相关性. 转化医学网（2017.6）
24. 乐飚, 宋毅，饶创宙，钱海龙，沈挺，张晓晶. 循环肿瘤细胞检测对胃癌辅助诊断和预后的意义. 转化医学网（2017.7）
25. 乐飚, 宋毅，邬振华，郝敬铎，沈挺，张晓晶. 循环肿瘤细胞检测对头颈部肿瘤诊疗的临床意义. 转化医学网（2017.9）
26. 乐飚, 宋毅，严梅娣，沈挺，张晓晶. 循环肿瘤细胞检测对乳腺癌早期诊断和预后的临床意义. 转化医学网（2017.11）
27. 张晓晶, 沈挺, 宋毅, 张凯岳. 微流控技术在液体活检领域的应用. 转化医学网（2018.1）
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